Group leader: Mariano Perales - Assistant Professor
Esta dirección de correo electrónico está siendo protegida contra los robots de spam. Necesita tener JavaScript habilitado para poder verlo. 910679164 - Ext: 79164 / 910679120 Ext:79120 ( Lab 135)


Plant development is coordinated with the environment to maximize growth and survival. We investigate mechanisms of plant response to environmental signals with the potential biotechnological application in agriculture.


Hypothesis: “Periodic genes are the first layer of environmental surveillance that guides plant developmental transitions, growth dynamics, and stress responses”


Our Approach: We investigate the function and molecular mechanism of periodic genes in poplar tree model. We apply genetics (CRISPR/Cas9), genomics, molecular and cell biology tools on poplar model tree. We focus on poplar homologs to Arabidopsis genes with roles in:


  1. Flowering time regulators
  2. Circadian clock regulators
  3. Light signaling mediators


Funding by:

2014. RYC-2012-10194 Ramón y Cajal program-MINECO
2014. PCIG13-GA-2013-631630 -2013 - WINCLOCK - European Commission
2019. PGC2018-093922-B-I00 – REACTIOn - MICIU




Hypothesis: “It is possible to bioengineer or biostimulate seasonal bud break and flowering in perennials”

Our Approach: We look for seasonal regulators and metabolites that promote shoot apical meristem growth reactivation. We focus on differential expressed genes, proteins, and metabolites obtained through:

  1. Transcriptomic and methylome studies
  2. Proteomic studies
  3. Non targeted metabolomic studies
  4. Chemical screening
  5. Plant phenological and biostimulation assays


Funding by:

2015. AGL2014-53352-R- MoDorCre - MECYT
2021. ERANET Suscrop 2-FruitFlow - European Commission





Representative Publications

Gómez-Soto, D., Allona, I., Perales, M. 2022. FLOWERING LOCUS T2 Promotes Shoot Apex Development and Restricts Internode Elongation via the 13-Hydroxylation Gibberellin Biosynthesis Pathway in Poplar. Frontiers in Plant Science 12. DOI: 10.3389/fpls.2021.814195

Gómez-Soto, D., Ramos-Sánchez, J.M., Alique, D., Conde, D., Triozzi, P.M., Perales, M., Allona, I. 2021. Overexpression of a SOC1-Related Gene Promotes Bud Break in Ecodormant Poplars. Frontiers in Plant Science 12. DOI: 10.3389/fpls.2021.670497

Ramos-Sánchez, J.M., Triozzi, P.M., Alique, D., Geng, F., Gao, M., Jaeger, K.E., Wigge, P.A., Allona, I., Perales, M. 2019. LHY2 Integrates Night-Length Information to Determine Timing of Poplar Photoperiodic Growth. Current Biology. DOI: 10.1016/j.cub.2019.06.003

Conde, D., Perales, M., Sreedasyam, A., Tuskan, G.A., Lloret, A., Badenes, M.L., González-Melendi, P., Ríos, G., Allona, I. 2019. Engineering Tree Seasonal Cycles of Growth Through Chromatin Modification. Frontiers in Plant Science 10. DOI: 10.3389/fpls.2019.00412

Maurya, J.P., Triozzi, P.M., Bhalerao, R.P., Perales, M. 2018. Environmentally Sensitive Molecular Switches Drive Poplar Phenology. Frontiers in Plant Science 9, 1873. DOI: 10.3389/fpls.2018.01873

Maurya, J.P., Triozzi, P.M., Bhalerao, R.P., Perales, M. 2018. Environmentally Sensitive Molecular Switches Drive Poplar Phenology. Frontiers in Plant Science 9. DOI: 10.3389/fpls.2018.01873

Triozzi, PM; Ramos-Sánchez, JM; Hernández-Verdeja, T; Moreno-Cortés, A; Allona, I; Perales, M. 2018. "Photoperiodic regulation of shoot apical growth in poplar". Frontiers in Plant Science. DOI: 10.3389/fpls.2018.01030".

Snipes, SA; Rodriguez, K; DeVries, AE; Miyawaki, KN; Perales, M; Xie, M; Reddy, GV. 2018. "Cytokinin stabilizes WUSCHEL by acting on the protein domains required for nuclear enrichment and transcription". PLoS Genetics. DOI: 10.1371/journal.pgen.1007351".

Conde, D; Moreno-Cortés, A; Dervinis, C; Ramos-Sánchez, JM; Kirst, M; Perales, M; González-Melendi, P; Allona, I. 2017. "Overexpression of DEMETER, a DNA demethylase, promotes early apical bud maturation in poplar". Plant, Cell & Environment. DOI: 10.1111/pce.13056".

Conde, D; Le Gac, A-L; Perales, M; Dervinis, C; Kirst, M; Maury, S; González-Melendi, P; Allona, I. 2017. "Chilling responsive DEMETER-LIKE DNA demethylase mediates in poplar bud break". Plant, Cell & Environment. DOI: 10.1111/pce.13019".

Ramos-Sánchez, JM; Triozzi, PM; Moreno-Cortés, A; Conde, D; Perales, M; Allona, I. 2017. "Real-time monitoring of PtaHMGB activity in poplar transactivation assays". Plant Methods. DOI: 10.1186/s13007-017-0199-x".

Rodriguez, K; Perales, M; Snipes, S; Yadav, RK; Diaz-Mendoza, M; Reddy, GV. 2016. "DNA-dependent homodimerization, sub-cellular partitioning, and protein destabilization control WUSCHEL levels and spatial patterning". Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.1607673113".

Perales, M; Rodriguez, K; Snipes, S; Yadav, RK; Diaz-Mendoza, M; Reddy, GV. 2016. "Threshold-dependent transcriptional discrimination underlies stem cell homeostasis". Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.1607669113".