Research overview

 

Plants have evolved remarkable strategies to survive and thrive in nearly every ecosystem on earth, including those shaped by agriculture. Understanding the molecular basis of these adaptive mechanisms is one of the major challenges in modern biology, and the central goal of the Adaptive Genomics and Genetics group.

 

We believe that uncovering the genes and proteins responsible for the variation we observe among plants today will empower us to breed better crops for the future.

 

Our group brings together expertise in genomics, genetics, molecular biology and physiology to study variation among wild and cultivated plants. Our models of choice go from Arabidopsis thaliana, where we study natural adaptation due to its global distribution across diverse environments to crops such as tomato, legumes, or grapevines, which offer rich opportunities to explore domestication and diversity of agricultural traits.

 

Research lines

 

Genomics of tomato domestication

Tomato is a powerful model for plant research, offering extensive genetic and genomic resources alongside remarkable phenotypic diversity resulting from its domestication (Figure 1). Our lab is using these resources to explore tomato diversity and investigate the effects of domestication and breeding.

 

 

Figure 1. Tomato phylogeny along domestication. Neighbor-joining tree of tomato accessions constructed from ~1800 genome-wide SNPs extracted from short read (~700 accessions) and microarray data (~1000 accessions). Color in each accession is determined by its passport data (gold color for accessions of unknown origin). Outside circles delimit sensible phylogenetic clades.

 

Tomato domestication: NUE

Most crops are bred under non-limiting nutrient conditions, resulting in a significant loss of genetic variation associated with nutrient use efficiency. Our lab works towards reducing the excessive input of fertilizers by improving nutrient uptake and assimilation under low or moderate nutrient supplies. To do this, we have identified diversity in NUE associated traits both in cultivated and wild tomatoes, highlighting different biological processes and physiological strategies regulating N responses. In addition, we have identified different QTLs associated to plant growth, yield, and fruit quality traits (N-QTLs) as well as candidate genes underlying them.

 

Figure 2. NUE diversity in tomato. Analysis of NUE related traits in a panel of commercial tomato varieties and wild relatives under deferent N supply (A-B). Identification of N-QTLs associated to plant growth, yield, and fruit quality traits (C) and candidate genes.

 

Tomato domestication: Circadian rhythms

Our lab showed that domestication delayed circadian rhythms in tomato through selection of knockout alleles of EID1 and LNK2, two light signaling genes (Figure 1). Our working hypothesis is that this modification of light signaling and circadian rhythms represent an advantage for tomato under the long days it encountered when it moved out of its equatorial origin. We are working towards demonstrating this hypothesis and characterizing the relationship between light signaling, circadian rhythms and plant performance.

 

 

Figure 3. Domestication delayed circadian rhythms in tomato. A) Mean relative position of cotyledon tip over time under constant light of 34 cultivated tomato accessions (red) and 44 S. pimpinellifolium accessions (yellow). Colored shading shows SEM; hatched areas in the background indicate subjective nights. Data from 8 independent experiments. B) Mean circadian period and phase estimates ± SEM (n = 2-5) of the genotypes shown in A). C) Genome-wide logarithm of the odds (LOD) scores from a QTL analysis on leaf movements for phase (red ) and period (black) in a S. pimpinellifolium x S. lycopersicum RIL population. The dashed horizontal line indicates the 5 % significance threshold. D) Mean period (left) and phase (right) estimates ± SEM of transgenic lines carrying wild (yellow) or cultivated (red) alleles of LNK2 (left) and EID1 (right). Stars indicate significant differences (one-way ANOVA and post-hoc Tukey’s HSD test, p < 0.01). E) Gene model representations for EID1 and LNK2 indicating the mutations found in cultivated tomato. F) frequency of mutations in EID1 and LNK2 shown in E) among accessions representing several domestication steps from left to right. Number of accessions of each group is indicated on the x axis.

 

Arabidopsis natural variation

Arabidopsis thaliana is an exceptionally adaptable plant found across the globe. Our lab studies its diversity in metabolic profiles and gene expression to uncover the genes and pathways that enable adaptation to natural challenges (Figure 4). Learning from strategies refined by nature over thousands of years, help us define sustainable solutions to protect our crops from future challenges.

 

Figure 4. Parallel evolution of salinity tolerance in Arabidopsis thaliana populations from the Cape Verde Islands. Plants from two islands on the Cape Verde archipelago have evolved independent mutations that disrupt the function of the Glycoside hydrolase family 38 gene (red and yellow). Both mutations trigger accumulation of glucuronyl-mannose, that protect the plants from salt stress.

 

Legumes: genetic diversity and molecular bases of drought and salt tolerance

We explore a diversity of legumes to identify varieties with enhanced drought tolerance and improved nitrogen fixation capacity. We focus on three species: Vicia sativa (common vetch), Cicer arietinum (chickpea), and Lens culinaris (lentil). To do this, we rely on some of the largest collections of these species, hosted in the Spanish Plant Genetic Resources Center (INIA-CSIC). In parallel, we are analyzing the impact of symbiotic interactions with nitrogen-fixing bacteria on stress tolerance. This is being addressed through integrated biochemical, physiological, and transcriptomic approaches to better understand the mechanisms that link symbiosis to stress resilience.

 

 

Figure 5. Dual approach to select drought tolerant legume varieties using natural genetic variation from genebanks.

 

Caballero Carretero, Patricia - Technician

González Delgado, Alberto - PhD Student

Jiménez Gómez, Jose María - Researcher CSIC

López Alejandre, Verónica - PhD Student

Martínez Rivas, Félix Juan - Postdoctoral Fellow

Medina Alcázar, Joaquín - Senior Researcher CSIC

Ramírez Parra, Elena - Researcher CSIC

Resuela Gonzalez, Jose Luis - PhD Student

Sánchez Rodríguez, Óscar - TFM Student

Zurita Crespo, Lucía - Technician

    • ATIDRAI_AGRO. Alianza Estratégica Transfronteriza para el Impulso y Desarrollo de Redes de Conocimiento de Investigación, Desarrollo e Innovación en el Sector Agroalimentario Transfronterizo: Mejora, Valorización y Conservación de Recursos Fitogenéticos 2026-2028 EU-Interreg POCTEP. IP. Juan Arqués

 

    • PHYTOLEARNING. MILLENIUM NUCLEUS IN DATA SCIENCE FOR PLANT RESILIENCE.  2025-2028. Núcleos Milenio en Ciencias Naturales y Exactas de la Agencia Nacional de Investigación y Desarrollo (ANID) PIs Elena Vidal, José Miguel Alvarez.

 

    • PID2023-151867OB-C33. CLIMVAR: UNLOCKING THE GENETIC DIVERSITY OF WILD TOMATO RELATIVES FOR CLIMATE-RESILIENT TOMATO BREEDING.  2024-2027. Ministerio de Ciencia, Innovación y Universidades/Agencia Estatal de Investigación (MICIU/AEI), Spain. PI: José M Jiménez-Gómez

 

    • CBGP-CEPLAS TOMATIME. TOMATIME: DOMESTICATION OF THE CIRCADIAN CLOCK IN TOMATO AND ITS EFFECT IN LIGHT AND TEMPERATURE STRESS RESPONSES. 2024-2027.  Ministerio de Ciencia, Innovación y Universidades/Agencia Estatal de Investigación (MICIU/AEI), Spain and Severo Ochoa Excellence program. PIs: José M Jiménez-Gómez and K. Wabnik.

 

    • SEP-210571680-862862-INCREASE. INTELLIGENT COLLECTIONS OF FOOD LEGUMES GENETIC RESOURCES FOR EUROPEAN AGROFOOD SYSTEMS.  2025-2027. H2020-EU. PI: R. Papa

  

    • REGEN. RED DE RECURSOS GENÉTICOS. 2025-2027. Ministerio de Ciencia, Innovación y Universidades/Agencia Estatal de Investigación (MICIU/AEI), Spain. IP: P. Revilla D. Grivet

 

    • PTI Agro4Food. RECOVERY OF PLANT GENETIC BIODIVERSITY. OPTIMIZATION OF AGRICULTURAL AND FORESTRY SYSTEMS. 2025-2027. Ministerio de Ciencia, Innovación y Universidades/Agencia Estatal de Investigación (MICIU/AEI), Spain. PIs: L. Guasch & R. Malvar

 

    • PATHFINDER-101098680. DARKWIN: POLLINATOR-ASSISTED PLANT NATURAL SELECTION AND BREEDING UNDER CLIMATE CHANGE PRESSURE. 2023-2026. European Innovation Council (EIC). PIs: F Pérez-Alfocea

 

    • Mision CBGP: EoI-MCBGP21. PLANTG_01_SUPERGREENFACTORIES. UNDERSTANDING HOW IMPORTANT PEST AND VIRAL DISEASES WILL EVOLVE IN THE CONTEXT OF CLIMATE CHANGE. 2022-2026. Ministerio de Ciencia, Innovación y Universidades/Agencia Estatal de Investigación (MICIU/AEI), Spain and Severo Ochoa Excellence program (CEX2020-000999-S). Coordinator: Araceli Diaz Perales

 

    • CDTI-IDI-20240292 BIOVID. EVALUACIÓN DEL GENOTIPADO DE NUEVA GENERACIÓN COMO HERRAMIENTA PARA LA IDENTIFICACIÓN DE BIOTIPOS DE VID ADAPTABLES A VARIACIONES AGROCLIMÁTICAS. 2024-2026. Centro para el Desarrollo Tecnológico y la Innovación. PIs: Viveros Villanueva

 

    • PID2020- 114165RR-C21. NUETOM: MOLECULAR ANALYSIS OF THE RESPONSES TO NITROGEN IN TOMATO GENOTYPES WITH CONTRASTING NUE. 2020-2025. Ministerio de Ciencia, Innovación y Universidades/Agencia Estatal de Investigación (MICIU/AEI), Spain. PI Joaquin Medina

 

    • PID2021-122138OR-I00. GREVISA: GENETIC RESOURCES OF VICIA SATIVA FOR A SUSTAINABLE AGRICULTURE. 2022-2025. Ministerio de Ciencia, Innovación y Universidades/Agencia Estatal de Investigación (MICIU/AEI), Spain. PI: Elena Ramírez-Parra

 

    • 2025AEP072-CSIC. GENETIC RESOURCES OF VICIA SATIVA FOR A SUSTAINABLE AGRICULTURE. 2025. Consejo Superior de Investigaciones Científicas, Spain. PI: ELENA RAMíREZ PARRA

 

    • Mision CBGP: EoI-MCBGP21. PLANTG_05_ROOTCLOCK. UNDERSTANDING HOW IMPORTANT PEST AND VIRAL DISEASES WILL EVOLVE IN THE CONTEXT OF CLIMATE CHANGE. 2022-2025. Ministerio de Ciencia, Innovación y Universidades/Agencia Estatal de Investigación (MICIU/AEI), Spain and Severo Ochoa Excellence program (CEX2020-000999-S).  Coordinator: Miguel Angel Moreno Risueño

 

    • RELEG RED2022-134237. LEGUMINOUS RESEARCH NETWORK. 2023 - 2025. Ministerio de Ciencia, Innovación y Universidades/Agencia Estatal de Investigación (MICIU/AEI,  Spain. IP: D. Rubiales

 

    • RED2022-134836-T. ROOTS FOR THE FUTURE: KNOW-HOW AND BIOTECHNOLOGICAL APPLICATIONS TO IMPROVE PRODUCTIVITY AND RESILIENCE UNDER STRESS CONDITIONS. 2023-2025. Ministerio de Ciencia, Innovación y Universidades/Agencia Estatal de Investigación (MICIU/AEI), Spain. PIs: Miguel Angel Moreno Risueño

 

    • CA22157.  RECROP. REPRODUCTIVE ENHANCEMENT OF CROP RESILIENCE TO EXTREME CLIMATE.  2023-2027. COST Euopean cooperation in science and Technology. PIs: Sotirios Fragkostefanakis  · Michal Lieberman‑Lazarovich, David Honys

Iannaccone, M., Xu, W., Gomez-Paez, D.-M., Choinard, S., Maricchiolo, E., Peaucelle, A., Voxeur, A., Haas, K.T., Lapierre, C., Jiménez-Gómez, J.M., Pompa, A., Magnani, E. 2026. A change in the cell wall status initiates the elimination of the nucellus in Arabidopsis. Proceedings of the National Academy of Sciences of the United States of America 123, e2515702123. DOI: 10.1073/pnas.2515702123

López-Román, M.I., De la Rosa, L., Castaño-Herrero, C., Marcos-Prado, M.T., Ramírez-Parra, E. 2026. Influence of genetic diversity, drought stress and rhizobial symbiosis on the nutritional quality of common vetch (Vicia sativa L.) grain. Journal of the Science of Food and Agriculture. DOI: 10.1002/jsfa.70410

Juan-Cabot, A., Carrillo, L., Fullana-Pericàs, M., Galmés, J., Medina, J., Conesa, M.À. 2025. Mediterranean Tomato Landraces Exhibit Genotype-Specific Transcriptomic Responses to Water Stress. Physiologia Plantarum 177, e70696. DOI: 10.1111/ppl.70696

González, J.M., Loarce, Y., Sánchez-Gordo, N., De la Rosa, L., Ramírez-Parra, E. 2025. Combining in vitro and Field Studies to Predict Drought Tolerance in Vicia sativa L. Genotypes. Plants 14. DOI: 10.3390/plants14213376

Gil-Villar, D., Arrones, A., Gramazio, P., Vilanova, S., Jiménez-Benavente, E., Plazas, M., Arbona, V., Granell, A., Medina, J., Molina, R.V., Prohens, J., Nebauer, S.G. 2025. Variation in responses to N limitation in Solanum lycopersicum var. cerasiforme and S. pimpinellifolium accessions and hybrids reveals genetic potential for improving nitrogen use efficiency (NUE) in tomato breeding. Plant Physiology and Biochemistry 229, 110428. DOI: 10.1016/j.plaphy.2025.110428

Landaeta-Sepúlveda, D., Johnson, N.R., Morales-Espinoza, J., Tobar, M., Sánchez, E., Fernández, J.D., Olivares-Yáñez, C., Medina, J., Canales, J., Vidal, E.A. 2025. Sulfate Deficiency-Responsive MicroRNAs in Tomato Uncover an Expanded and Functionally Integrated Regulatory Network. International Journal of Molecular Sciences 26, 8392. DOI: 10.3390/ijms26178392

Caballero-Carretero, P., Medina, J. 2025. A mobile transcription factor coordinates systemic responses to nitrogen deficiency. Nature Plants 11, 717–724. DOI: 10.1038/s41477-025-02059-w

Martínez Rivas, F.J., Wozny, D., Xue, Z., Gilbault, E., Sapir, T., Rouille, M., Ricou, A., Medina, J., Noël, L.D., Lauber, E., Voxeur, A., Mazier, M., Loudet, O., Clément, G., Jiménez-Gómez, J.M. 2025. Parallel evolution of salinity tolerance in Arabidopsis thaliana accessions from Cape Verde Islands. Science Advances 11, eadq8210. DOI: 10.1126/sciadv.adq8210

López-Román, M.I., Castaño-Herrero, C., De la Rosa, L., Ramírez-Parra, E. 2025. Optimizing Nitrogen Fixation in Vicia sativa: The Role of Host Genetic Diversity. Agronomy 15, 1479. DOI: 10.3390/agronomy15061479

Contreras-Riquelme, J.S., Contreras, M., Moyano, T.C., Sjoberg, R., Jimenez-Gomez, J., Alvarez, J.M. 2025. Desert-adapted tomato Solanum pennellii exhibit unique regulatory elements and stress-ready transcriptome patterns to drought. PLOS ONE 20, e0324724. DOI: 10.1371/journal.pone.0324724

González-Delgado, A., Martínez-Rivas, F.J., Jiménez-Gómez, J.M. 2025. Photoperiod insensitivity in crops. Journal of Experimental Botany eraf153. DOI: 10.1093/jxb/eraf153

Mohammadi, V., Rezaeizadeh, A., Mondak, B., Rasoulnia, A., Domínguez-Figueroa, J., Carrillo, L., Romero-Hernandez, G., Medina, J. 2025. Unraveling the role of autophagy and antioxidants in anther and pistil responses to heat stress in rapeseed (Brassica napus L.). Plant Cell Reports 44, 51. DOI: 10.1007/s00299-025-03437-6

Glaus, A.N., Brechet, M., Swinnen, G., Lebeigle, L., Iwaszkiewicz, J., Ambrosini, G., Julca, I., Zhang, J., Roberts, R., Iseli, C., Guex, N., Jiménez-Gómez, J., Glover, N., Martin, G.B., Strickler, S., Soyk, S. 2025. Repairing a deleterious domestication variant in a floral regulator gene of tomato by base editing. Nature Genetics 1–11. DOI: 10.1038/s41588-024-02026-9

Xue, Z., Ferrand, M., Gilbault, E., Zurfluh, O., Clément, G., Marmagne, A., Huguet, S., Jiménez-Gómez, J.M., Krapp, A., Meyer, C., Loudet, O. 2024. Natural variation in response to combined water and nitrogen deficiencies in Arabidopsis. The Plant Cell koae173. DOI: 10.1093/plcell/koae173

Renau-Morata, B., Jiménez-Benavente, E., Gil-Villar, D., Cebolla-Cornejo, J., Romero-Hernández, G., Carrillo, L., Vicente-Carbajosa, J., Medina, J., Molina, R.V., Nebauer, S.G. 2024. Arabidopsis CDF3 transcription factor increases carbon and nitrogen assimilation and yield in trans-grafted tomato plants. Plant Physiology and Biochemistry 210, 108607. DOI: 10.1016/j.plaphy.2024.108607

Pérez-Alfocea, F., Borghi, M., Guerrero, J.J., Jiménez, A.R., Jiménez-Gómez, J.M., Fernie, A.R., Bartomeus, I. 2024. Pollinator-assisted plant phenotyping, selection, and breeding for crop resilience to abiotic stresses. The Plant Journal. DOI: 10.1111/tpj.16748

López-Román, M.I., De la Rosa, L., Marcos-Prado, T., Ramírez-Parra, E. 2024. Cross-Species Transferability of SSR Markers for Analyzing Genetic Diversity of Different Vicia species Collections. Agronomy 14, 326. DOI: 10.3390/agronomy14020326

Renau-Morata, B., Cebolla-Cornejo, J., Carrillo, L., Gil-Villar, D., Martí, R., Jiménez-Gómez, J.M., Granell, A., Monforte, A.J., Medina, J., Molina, R.V., Nebauer, S.G. 2024. Identification of Solanum pimpinellifolium genome regions for increased resilience to nitrogen deficiency in cultivated tomato. Scientia Horticulturae 323, 112497. DOI: 10.1016/j.scienta.2023.112497

Álvarez-Aragón, R., Palacios, J.M., Ramírez-Parra, E. 2023. Rhizobial symbiosis promotes drought tolerance in Vicia sativa and Pisum sativum. Environmental and Experimental Botany 208, 105268. DOI: 10.1016/j.envexpbot.2023.105268

Ramírez-Parra, E., De la Rosa, L. 2023. Designing Novel Strategies for Improving Old Legumes: An Overview from Common Vetch. Plants 12, 1275. DOI: 10.3390/plants12061275

Mandakovic, D., Aguado-Norese, C., García-Jiménez, B., Hodar, C., Maldonado, J.E., Gaete, A., Latorre, M., Wilkinson, M.D., Gutiérrez, R.A., Cavieres, L.A., Medina, J., Cambiazo, V., Gonzalez, M. 2023. Testing the stress gradient hypothesis in soil bacterial communities associated with vegetation belts in the Andean Atacama Desert. Environmental Microbiome 18, 24. DOI: 10.1186/s40793-023-00486-w

Carrillo, L., Baroja-Fernández, E., Renau-Morata, B., Muñoz, F.J., Canales, J., Ciordia, S., Yang, L., Sánchez-López, Á.M., Nebauer, S.G., Ceballos, M.G., Vicente-Carbajosa, J., Molina, R.V., Pozueta-Romero, J., Medina, J. 2023. Ectopic expression of the AtCDF1 transcription factor in potato enhances tuber starch and amino acid contents and yield under open field conditions. Frontiers in Plant Science 14. DOI: 10.3389/fpls.2023.1010669

Canales, J., Arenas-M, A., Medina, J., Vidal, E.A. 2023. A Revised View of the LSU Gene Family: New Functions in Plant Stress Responses and Phytohormone Signaling. International Journal of Molecular Sciences 24, 2819. DOI: 10.3390/ijms24032819

Xiang, Y., Sapir, T., Rouillard, P., Ferrand, M., Jiménez-Gómez, J.M. 2022. Interaction between photoperiod and variation in circadian rhythms in tomato. BMC Plant Biology 22, 187. DOI: 10.1186/s12870-022-03565-1

Uribe, F., Henríquez-Valencia, C., Arenas-M, A., Medina, J., Vidal, E.A., Canales, J. 2022. Evolutionary and Gene Expression Analyses Reveal New Insights into the Role of LSU Gene-Family in Plant Responses to Sulfate-Deficiency. Plants 11, 1526. DOI: 10.3390/plants11121526

Contreras-López, O., Vidal, E.A., Riveras, E., Alvarez, J.M., Moyano, T.C., Sparks, E.E., Medina, J., Pasquino, A., Benfey, P.N., Coruzzi, G.M., Gutiérrez, R.A. 2022. Spatiotemporal analysis identifies ABF2 and ABF3 as key hubs of endodermal response to nitrate. Proceedings of the National Academy of Sciences 119. DOI: 10.1073/pnas.2107879119

De la Rosa, L., López-Román, M.I., González, J.M., Zambrana, E., Marcos-Prado, T., Ramírez-Parra, E. 2021. Common Vetch, Valuable Germplasm for Resilient Agriculture: Genetic Characterization and Spanish Core Collection Development. Frontiers in Plant Science 12, 282. DOI: 10.3389/fpls.2021.617873

Renau-Morata, B., Molina, R.-V., Minguet, E.G., Cebolla-Cornejo, J., Carrillo, L., Martí, R., García-Carpintero, V., Jiménez-Benavente, E., Yang, L., Cañizares, J., Canales, J., Medina, J., Nebauer, S.G. 2021. Integrative Transcriptomic and Metabolomic Analysis at Organ Scale Reveals Gene Modules Involved in the Responses to Suboptimal Nitrogen Supply in Tomato. Agronomy 11, 1320. DOI: 10.3390/agronomy11071320

De la Rosa, L., Zambrana, E., Ramirez-Parra, E. 2020. Molecular bases for drought tolerance in common vetch: designing new molecular breeding tools. BMC Plant Biology 20, 71. DOI: 10.1186/s12870-020-2267-z

Domínguez, M., Dugas, E., Benchouaia, M., Leduque, B., Jiménez-Gómez, J.M., Colot, V., Quadrana, L. 2020. The impact of transposable elements on tomato diversity. Nature Communications 11, 4058. DOI: 10.1038/s41467-020-17874-2

Zhang, L., Jiménez-Gómez, J.M. 2020. Functional analysis of FRIGIDA using naturally occurring variation in Arabidopsis thaliana. The Plant Journal 103, 154–165. DOI: 10.1111/tpj.14716

Van Dooren, T.J.M., Silveira, A.B., Gilbault, E., Jiménez-Gómez, J.M., Martin, A., Bach, L., Tisné, S., Quadrana, L., Loudet, O., Colot, V. 2020. Mild drought in the vegetative stage induces phenotypic, gene expression, and DNA methylation plasticity in Arabidopsis but no transgenerational effects. Journal of Experimental Botany 71, 3588–3602. DOI: 10.1093/jxb/eraa132

Yuste-Lisbona, F.J., Fernández-Lozano, A., Pineda, B., Bretones, S., Ortíz-Atienza, A., García-Sogo, B., Müller, N.A., Angosto, T., Capel, J., Moreno, V., Jiménez-Gómez, J.M., Lozano, R. 2020. ENO regulates tomato fruit size through the floral meristem development network. Proceedings of the National Academy of Sciences 117, 8187–8195. DOI: 10.1073/pnas.1913688117

Hu, Y., Mesihovic, A., Jiménez-Gómez, J.M., Röth, S., Gebhardt, P., Bublak, D., Bovy, A., Scharf, K.-D., Schleiff, E., Fragkostefanakis, S. 2020. Natural variation in HsfA2 pre-mRNA splicing is associated with changes in thermotolerance during tomato domestication. New Phytologist 225, 1297–1310. DOI: 10.1111/nph.16221

García-Jiménez, B., Muñoz, J., Cabello, S., Medina, J., Wilkinson, M.D. 2020. Predicting microbiomes through a deep latent space. Bioinformatics. DOI: 10.1093/bioinformatics/btaa971

Domínguez-Figueroa, J., Carrillo, L., Renau-Morata, B., Yang, L., Molina, R.-V., Marino, D., Canales, J., Weih, M., Vicente-Carbajosa, J., Nebauer, S.G., Medina, J. 2020. The Arabidopsis Transcription Factor CDF3 Is Involved in Nitrogen Responses and Improves Nitrogen Use Efficiency in Tomato. Frontiers in Plant Science 11, 1825. DOI: 10.3389/fpls.2020.601558

Coleto, I., Bejarano, I., Marín‐Peña, A.J., Medina, J., Rioja, C., Burow, M., Marino, D. 2020. Arabidopsis thaliana transcription factors MYB28 AND MYB29 shape ammonium stress responses by regulating fe homeostasis. New Phytologist. DOI: 10.1111/nph.16918

Canales, J., Uribe, F., Henríquez-Valencia, C., Lovazzano, C., Medina, J., Vidal, E.A. 2020. Transcriptomic analysis at organ and time scale reveals gene regulatory networks controlling the sulfate starvation response of Solanum lycopersicum. BMC Plant Biology 20, 385. DOI: 10.1186/s12870-020-02590-2

Renau-Morata, B., Carrillo, L., Cebolla-Cornejo, J., Molina, R.V., Martí, R., Domínguez-Figueroa, J., Vicente-Carbajosa, J., Medina, J., Nebauer, S.G. 2020. The targeted overexpression of SlCDF4 in the fruit enhances tomato size and yield involving gibberellin signalling. Scientific Reports 10, 10645. DOI: 10.1038/s41598-020-67537-x

Renau-Morata, B., Carrillo, L., Dominguez-Figueroa, J., Vicente-Carbajosa, J., Molina, R.V., G. Nebauer, S., Medina, J. 2020. CDF transcription factors: plant regulators to deal with extreme environmental conditions. Journal of Experimental Botany. DOI: 10.1093/jxb/eraa088

Huertas, R., Catalá, R., Jiménez-Gómez, J.M., Mar Castellano, M., Crevillén, P., Piñeiro, M., Jarillo, J.A., Salinas, J. 2019. Arabidopsis SME1 Regulates Plant Development and Response to Abiotic Stress by Determining Spliceosome Activity Specificity. The Plant Cell 31, 537–554. DOI: 10.1105/tpc.18.00689

Fantini, E., Sulli, M., Zhang, L., Aprea, G., Jiménez-Gómez, J.M., Bendahmane, A., Perrotta, G., Giuliano, G., Facella, P. 2019. Pivotal Roles of Cryptochromes 1a and 2 in Tomato Development and Physiology. Plant Physiology 179, 732–748. DOI: 10.1104/pp.18.00793

Alvarez, J.M., Moyano, T.C., Zhang, T., Gras, D.E., Herrera, F.J., Araus, V., O’Brien, J.A., Carrillo, L., Medina, J., Vicente-Carbajosa, J., Jiang, J., Gutiérrez, R.A. 2019. Local Changes in Chromatin Accessibility and Transcriptional Networks Underlying the Nitrate Response in Arabidopsis Roots. Molecular Plant. DOI: 10.1016/j.molp.2019.09.002