News 2020



- Wednesday, 14 October 2020

Susanna Manrubia (CNB-CSIC) has been nominated External Advisor of the Computational/Systems Biology and Genomics Program (CsBGP) of the CBGP

Susanna Manrubia is an internationally recognized expert in developing theoretical and computational models for the evolution of molecular populations, and in the quantitative analysis of adaptive and evolutionary mechanisms. She will provide scientific advice on CsBGP program launched with Severo Ochoa Centre of Excellence Grant of the CBGP (UPM-INIA).
 


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- Thursday, 08 October 2020

2020 Nobel Prize in Chemistry: CRISPR/Cas9

The 2020 Chemistry Nobel prize was awarded yesterday to Emmanuelle Charpentier and Jennifer A. Doudna for the discovery of the CRISPR/Cas9 genetic scissors.
 


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- Monday, 05 October 2020

The Centre of Excellence for Plant-Environment Interactions (CEPEI) announces the result of its first call for collaborative research projects

CEPEI is a joint research and innovation initiative between three centres of excellence: Spain’s CBGP (UPM-INIA), and the Chinese Academy of Science’s IGDB and PSC. In this first CEPEI call, five projects (EoIs) have been granted to develop joint, collaborative initiatives between researchers from CBGP (UPM-INIA) located in Madrid (Spain) and IGDB based in Beijing and PSC operating from Shanghai (China).


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- Tuesday, 22 September 2020

Researchers from CBGP, CTB, and IDSSC are working on the development of a Covid-19 diagnostic kit

The research group of Dr. Araceli Diaz-Perales from the Center for Plant Biotechnology and Genomics (CBGP, UPM-INIA), a joint center of the UPM and INIA, together with the Laboratory of Óptica, Fotónica y Biofotónica (GOFB) of the Centre of Biomedical Technologies de Tecnología Biomédica (CTB, UPM), and in collaboration with the Health Institute of San Carlos Clinical Hospital (IDSSC) and the National Biotechnology Center (CNB-CSIC), have been working since March on improving the diagnosis of Covid-19 and developing a new kit that is more complete and cheaper than the current ones.


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- Monday, 21 September 2020

Which genes determine fungal life-style in the interaction with plants?

The fungus Plectosphaerella cucumerina is a pathogen of some crops and a model organism for the study of Arabidopsis thaliana basal and nonhost resistance to necrotrophic fungi. In this work, researchers of the Plant Innate Immunity and Resistance to Necrotrophic Fungi group of CBGP have sequenced and compared the genomes and transcriptomes of three Plectosphaerella strains. They demonstrate that the diverse lifestyles and pathogenicity of these strains are determined by the expression of specific fungal and plant genes at early stages of colonization. The Plectosphaerella spp. genomes and transcriptomes described in this article are the first published of this fungal species and also the first genomic project of plant fungal pathogens led by CBGP researchers.


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- Friday, 11 September 2020

MtCOPT2 is a mycorrhiza-specific copper transporter

In this work, we study the first metal transporter specific of a symbiosis essential for growth of 85% terrestrial plants in natural environments and for sustainable productivity of most crops.
 


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- Monday, 07 September 2020

Angel Goñi-Moreno joins the new Synthetic Biology and Bioengineering Program of the CBGP to lead the new Biocomputing group

Dr. Angel Goñi-Moreno joins the new CBGP Synthetic Biology and Bioengineering program, and establishes the Biocomputation Lab. He comes from Newcastle University (UK), where he has been Principal Investigator since 2016. Previous to this, Dr. Goñi-Moreno spend 6 years of postdoctoral experience in Manchester Metropolitan University (UK) and the National Centre for Biotechnology CNB-CSIC (Spain). His work sits at the interface of computing and biology, aiming at engineering biological systems with human-defined information processing abilities.


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- Tuesday, 01 September 2020

Dsup, a protein unique to tardigrades, protects DNA from radiation: How does it do it?

Dsup, a protein unique to tardigrades, protects DNA from damage produced by radiation and radicals. We present the first computational study on the Dsup-DNA interaction at atomic detail. Our results suggest that Dsup adjusts its structure to fit DNA's shape providing an electric shielding which could be paramount in protecting DNA from radiation.


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- Monday, 31 August 2020

Metal nicotianamine transporter MtYSL3 delivers iron and zinc for nitrogen fixation

The iron and zinc delivered by the YSL3 protein is used in symbiotic nitrogen fixation in legume root nodules, one of the main sustainable alternatives to the overuse of nitrogen fertilizers.
 


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- Tuesday, 25 August 2020

Antonio Molina (CBGP Director) joints the new SOMM alliance Executive Board as Executive Director

Four new delegates and a new executive director will design and execute in coordination with the presidency the strategies for communication, visibility, I+D+i, global impact and intitutional relations.


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- Monday, 03 August 2020

How virus infections alter plant developmental traits. A case study of flower stalk elongation

The virus-induced alteration in the developmental pattern of the flower stalk is associated to the kind of intracellular dynamics of a non-structural viral protein, which is governed by the change in a single amino acid of the protein.


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- Friday, 24 July 2020

Open Statement of EUSAGE (European Sustainable Agriculture Through Genome Editing)

Agriculture and food production must become more sustainable in a world facing an increasing, more affluent world population, climate change, and environmental degradation.
 


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- Tuesday, 07 July 2020

New CBGP (UPM-INIA) Directory Board appointed

The new CBGP (UPM-INIA) Directory Board which will jointly supervise and support the activities of CBGP was appointed on February 12th, 2020 for the 4 years-term.


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- Thursday, 02 July 2020

Wheat: a strategic crop to feed world increasing population

CBGP (UPM-INIA) initiates a strategic research and innovation program on wheat. This research will generate new wheat varieties with better adaptation to environment conditions and enhance disease resistance to pathogens.
 


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- Wednesday, 01 July 2020

SlCDF4 as a new key factor controlling tomato size and composition

Tomato is one of the most widely cultivated vegetable crops and a model for studying fruit biology. Although several genes involved in the traits of fruit quality, development and size have been identified, little is known regulatory genes controlling its growth.


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- Monday, 29 June 2020

TOMAS RUIZ ARGÜESO: Brief sketch of a life among rhizobia

Tomas Ruiz Argüeso (Villamol 1943 - Madrid 2020) was Full Professor of Microbiology and, until his death, Emeritus Professor at CBGP and Department of Biotechnology-Plant Biology at the Universidad Politécnica de Madrid.

 


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- Friday, 19 June 2020

How roots of crops adapt to climate change?

Plant roots are responsible for water and nutrients uptake, but changes in soil temperatures associated to climate change alters this process limiting crop growth. Root traits for adaptation to this stress are being used to obtain better crops. In this review, we have summarized the current knowledge about these traits and their impact on yield.


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- Wednesday, 17 June 2020

Atomic structure of the most critical protein for global nitrogen fixation determined

The 3D atomic structure of the nitrogenase cofactor maturase NifB has been solved at high resolution uncovering a unique mechanism to control formation of highly reactive radical species by the protein.


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- Tuesday, 16 June 2020

The cell wall research of CBGP “Plant Innate Immunity and Resistance to Necrotrophic Fungi” group highlighted by The American Phytopathological Society (APS)

Antonio Molina and his research group aimed to understand the role of the cell wall in the regulation of plant resistance responses to pathogens in a study published in the Molecular Plant-Microbe Interactions. Cell wall research presents the possibility of a simple and sustainable method to protect crops. To do that, a collection of mutants with alterations on their cell walls composition/structure was selected and their resistance to different pathogens analyzed. This great achievement allowed to identify the novel disease resistance mechanisms mediated by the cell wall and opened new avenues for developing novel technologies for sustainable agriculture.


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- Monday, 15 June 2020

The regulation of germination: an updated guide for researchers

The ability of a seed to germinate and establish a plant at the correct time of year is of vital importance from an ecological and economic point of view. This paper reviews the mechanisms that regulate this capacity and its dependence on the interaction between the genetic composition of seeds and environmental factors.


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- Tuesday, 09 June 2020

Dr. Andrea Sánchez Vallet joins the Interactions of Plants with Environment (IPM) program of the CBGP (UPM-INIA)

Her research aims to understand the molecular bases involved in the interaction between plants and potential pathogens and to determine the key pathogen components that are involved in host colonization.
 


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- Monday, 08 June 2020

Seed dormancy and chemical modifications of nucleic acids

This review focuses on new mechanisms of controlling gene expression during seed dormancy: the oxidation and methylation of the mRNA and DNA. The biological significance of these chemical modifications upon seed development is discussed.


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- Tuesday, 02 June 2020

Dr. Isidro-Sánchez joins the new CsBGP, Computational Systems Biology and Genomics program with a Senior Beatriz Galindo position.

CBGP is pleased to introduce Julio Isidro-Sánchez a newly appointed senior group leader. His background is in plant breeding, crop genomics, and crop physiology. His Ph.D. was focused on the role of breeding on the physiological traits of durum wheat under Mediterranean conditions.


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- Friday, 29 May 2020

Tolerance: A key plant defense against pathogens

Israel Pagán and Fernando García-Arenal review the conceptual basis of tolerance and discuss the abundant evidence supporting the key role tolerance as a plant defense mechanism against pathogens.


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- Wednesday, 27 May 2020

CBGP team awarded Chan Zuckerberg grant to support scientific software for phylogenomic analysis

Today, CBGP (UPM-INIA) researcher Dr. Huerta-Cepas was awarded with a grant from the Chan Zuckerberg Initiative (CZI) to support open source software essential to scientific research.


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- Monday, 25 May 2020

PlantResponse Biotech, a spin-off of the CBGP (UPM-INIA), leads AgBiotech investment in Europe in 2019

The Agri-FoodTech investment continues to break records across the world, reaching $20 billion in 2019, up more than 6-fold the 2012. Investment. PlantResponse Biotech SL has been listed among the top Agribusiness market investments in Europe and Spain in 2019.


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- Tuesday, 12 May 2020

Identified a transporter that delivers iron to symbiotic nitrogen-fixing bacteria in root nodules

The iron delivered by the FPN2 protein is used in symbiotic nitrogen fixation in legume root nodules, one of the main sustainable alternatives to the overuse of nitrogen fertilizers.


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- Thursday, 23 April 2020

Progress toward the isolation of "hidden" cell populations of dark-growing organs

High-resolution, cell type-specific analysis of gene expression greatly enhances the understanding of developmental regulation and responses to external stimuli in any multicellular organism. A critical step for analyzing cell types using transcriptomics is the efficient isolation of the cell types of interest.


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- Monday, 20 April 2020

Plant defences against Tetranychus urticae: mind the gaps

Plant defences against phytophagous arthropods include multiple molecular events, since the perception to the final synthesis of defensive compounds. This review deals with teh current knowledge of these events in teh palnt-Tetranychus urtice (spider mite) interaction, focusing in the still unknown gaps.


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- Wednesday, 15 April 2020

Computational analyses unveil key amino acids of lipid antigen-presenting proteins in the initial stages of allergen recognition

The molecular recognition that triggers the immune response to allergens start at the loading of molecules onto antigen-presenting proteins that activate T-cell receptors. CD1d is the protein in charge of presenting lipid antigens to iNKT cells. Our computational study identified CD1d amino acids with a potential key role in that initial loading.


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- Monday, 13 April 2020

Novel Genome Editing Technologies: first report of consumers attitude towards the use of these technologies

The Norwegian GENEinnovate consortium has published the first report on Norwegian consumers attitudes towards the use of gene editing in livestock and crop plants in Norwegian agriculture and aquaculture.
 


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- Tuesday, 07 April 2020

Structural clues for unraveling the first stage of lipid-antigen presentation in immune responses to allergies

The complex response of the human immune system to the presence of hazardous molecules is triggered through their recognition by T-cell receptors facilitated by antigen-presenting proteins. We have found structural clues of the lipid-presenting CD1d protein that may help elucidate the mechanism of initial lipid-loading stages of the whole process.


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- Friday, 03 April 2020

FIRST COLLABORATIVE PROJECTS CALL OF THE SINO SPANISH CENTER OF EXCELLENCE FOR PLANT-ENVIRONMENT INTERACTIONS (CEPEI)

The Center of Excellence for Plant-Environment Interactions (CEPEI), an international research center created to maximize the synergies between Centro de Biotecnología y Genómica de Plantas (CBGP, UPM-INIA) SPAIN, the Institute of Genetics and Developmental Biology of Beijing (IGDB) CHINA and the Shanghai Centre for Plant Stress Biology (PSC) CHINA announces the first CEPIE´s collaborative projects call.


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- Wednesday, 01 April 2020

Insights into the function of the new chromatin remodeling complex in plants

Chromatin remodeling processes play essential roles in the regulation of various physiological processes in plants through changes in gene expression. In this work we discuss recent progress in understanding a mechanism of chromatin reorganization, NuA4-mediated histone acetylation, which operates in plant species as well as in other eukaryotes.


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- Thursday, 26 March 2020

CBGP researchers support AseBio manifest for biotechnology and life sciences

In light of the COVID-19 global outbreak, Spain should invest in the promotion of science and innovation more than ever. Nowadays, the importance and impact of biotechnology on all areas of life is evident, therefore, an emerging initiative of the Asociación Española de Bioempresas, AseBio remains very timely and calls for collective support from scientific institutions across the country. CBGP fully supports the AseBio manifest and several CBGP researchers already signed it to express their support of the cause.




- Monday, 23 March 2020

The CBGP gets a grant to acquire new equipment for its Systems Biology and Modelling Lab (SysBioM)

CBGP (UPM-INIA) has received recently a competitive grant from the Spanish Research Agency/Ministry of Science and Innovation for setting-up a new scientific infrastructure, the Systems Biology and Biological Modeling lab (SysBioM). The center will invest this grant resources in the acquisition of state-of-the-art instruments of the SysBioM, which is integrated into its Computational/Systems Biology and Genomics Program (CsBGP) of the CBGP (UPM-INIA).


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- Thursday, 19 March 2020

The suitability of plants against new human virus diseases, also against coronaviruses

The use of plants as biofactories allows the production of very high amounts of human virus proteins suited for the quick development of vaccines and diagnostic tools


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- Thursday, 19 March 2020

Pathogen emergence: virus infections cannot be isolated from their environment

How does the environment influence the transmission dynamics and emergence of pathogens? A new study of plant-virus infections suggests the organization of ecosystems is flexible and adapts to environmental changes.


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- Wednesday, 04 March 2020

The poly(A) site selection and the salicylic acid signaling modulate the responses to low nitrogen availability

Nitrogen (N) is an essential nutrient for plant growth and production. For plant improvement, we need to identify and understand the mechanisms that plants have evolved to cope with N deficiency. Here, we have identified novel molecular mechanisms that connect N starvation responses with alternative polyadenylation and salicylic acid signaling


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- Wednesday, 04 March 2020

New functions of CDF factors in the regulation of plant growth and metabolism

In terrestrial environments, water and nutrient availabilities and temperature conditions are highly variable, and especially in extreme environments limit survival, growth and reproduction of plants. In this work it is described the multifaceted role of CDF factors acting on both flowering time and abiotic stress tolerance.


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- Friday, 28 February 2020

CBGP researchers discover a gene that regulates plants’ disease resistance and cell wall composition

Plant diseases have devastating consequences on crops, causing losses of up to 30% of yield. Plants have developed a robust immune system that allows them to defend against pathogens and pests. This article of CBGP (UPM-INIA) support the role of plant cell wall as an essential component of plants immune system.


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- Thursday, 27 February 2020

Nicotianamine-enabled iron delivery for nitrogen fixation

Iron delivered by the NAS2 protein is used by legume nodules to carry out nitrogen fixation, one of the main sustainable alternatives to the overuse of nitrogen fertilizers.


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- Tuesday, 25 February 2020

The CBGP organizes the CBGP_S3-Forum on “Novel Genome Editing Technologies: Evolution and Revolution”

The CBGP (UPM-INIA) organizes, in the frame of its new CBGP_S3-Forum Program, the Workshop “Novel Genome Editing Technologies: Evolution and Revolution” that aims to discuss about the potential of Genome Editing technology and the different legal policies and scenarios to commercialize genome-edited products.


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- Friday, 21 February 2020

The weakening of endosperm cell walls is mediated by mannanases secreted from the aleurone layer of germinating barley seeds

Cereal seeds (wheat, rice, maize, barley...) constitute the first world crop. In this work, it is described that mannans are particularly abundant in barley seeds and the study of mannanases and mannan mobilization during germination is determinant in the control of this process.


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- Tuesday, 18 February 2020

Designing new molecular breeding tools for strategies of drought tolerance in Vicia

Common vetch is a legume with high content of vegetable protein. This crop is relevant in sustainable agriculture systems by avoiding the use of nitrogen fertilizers, reducing CO2 emissions and other pollutants.


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- Monday, 10 February 2020

Proof that chloroplasts can host active Nitrogenase

The Caro and Rubio labs, in the context of the "BNF Cereals" Bill & Melinda Gates Foundation project, show that tobacco can be engineered to produce active Nitrogenase Fe protein in chloroplasts.
 


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- Friday, 07 February 2020

The First Spanish/Chinese Workshop "Centre of Excellence for Plant-Environment Interactions (CEPEI)”

CEPEI, a newly established international research center created to maximise the synergies between Centro de Biotecnología y Genómica de Plantas (CBGP, UPM-INIA), the Institute of Genetics and Developmental Biology (IGDB) and the Shanghai Centre for Plant Stress Biology (PSC) organizes the First Spanish/Chinese Workshop that will take place in Madrid on the 2nd March 2020. Rescheduled to the second half of May.


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- Thursday, 06 February 2020

Harnessing beneficial plant-fungus interactions to confront climate change effects

To confront global climate change effects, agricultural innovations must be embraced. To achieve maximum improvements, the agricultural innovations should not focus on the crop side alone, but rather pursue a holistic approach including the entire ecosystem. Here, we discuss how plant-fungus interactions can be used to optimize crop productivity.
 


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- Friday, 31 January 2020

The CBGP (UPM-INIA) celebrates the International Day of Women and Girls in Science with a contest and at event at the centre facilities on February 11

On the occasion of the International Day of Women and Girls in Science (February 11, 2020), the Center for Plant Biotechnology and Genomics, CBGP (UPM-INIA), organizes the first contest of drawing and short stories, and the CBGP S3-Forum on “ WOMEN AND GIRL'S DAY IN SCIENCE: R&D for a more sustainable agriculture and food quality”.


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- Wednesday, 29 January 2020

Biosynthesis of Nitrogenase Cofactors

Research in the laboratory of Prof. Luis Rubio aims at understanding the biochemical processes and mechanisms that enable biological N2 fixation, the reduction of inert N2 gas into ammonia. A long-term goal of this research, supported by the Bill & Melinda Foundation, is to obtain crops that can utilize atmospheric N2 as direct nitrogen source, minimizing the need of synthetic nitrogen fertilizers, one of the main expenses for farmers and prohibitively so in developing countries, and reducing the negative environmental effects that originates from fertilizer production and use.


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- Monday, 20 January 2020

Biocontrol capabilities of the genus Serratia for sustainable agriculture: Enterobacteria with a unique secondary metabolism

Serratia are enterobacterias, widely diverse and occupying many different habitats such as water, soil, plants, vertebrates and humans. They share a rich secondary metabolism and are able to produce a wide range of natural bioactive products including the β-lactam antibiotic carbapenem or the antifungal compound oocydin A.


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- Thursday, 09 January 2020

Advances deciphering the epigenome of plants

Epigenetic regulation in plants has enormous implications for crop improvement and agriculture. Researchers at Centro de Biotecnología y Genómica de Plantas (CBGP, UPM-INIA) used next-generation sequencing approaches and novel computational analytical pipelines to describe the genome-wide map of an epigenetic mark in a Brassica crop.


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Centre for Plant Biotechnology and Genomics UPM – INIA Parque Científico y Tecnológico de la U.P.M. Campus de Montegancedo
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